Hycult Biotech

C5L2, Mouse, Peptide

Product Description

  • The orphan receptor C5L2 (also known as gpr77), which shares 35% amino identity with CD88, is a promiscuous complement fragment-binding protein. C5L2 binds C5a with high affinity. It has a 10-fold higher affinity for C5a desArg than CD88. C5L2 also has an affinity for C4a and C3a, and their metabolites C4a desArg and C3a desArg. C3a binds at a side distinct from the C5a binding site. Unlike other chemoattractant receptors C5L2 couples poorly to the intracellular signalling and internalisation machinery. The mouse C5L2 peptide is a N-terminal peptide (2-28) and has the following amino acid sequence: MMNHTTSEYYDYEYDHEHYSDLPDVPVDC.

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Product Number Description Package Size List Price (CAD)
HYBHC1103 C5L2, Mouse, Peptide 10 µg
CA$721.00
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