EpiCypher

Nucleosome, Recombinant Human, H2AK15ub1 dNuc, Biotinylated

  • Supplier: EpiCypher
  • Storage Conditions: Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.

Product Description

  • Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P20671; H2B-O60814; H3.1-P68431; H4-P62805) wrapped by 147 base pairs of 601 positioning sequence DNA. Histone H2A (created by a proprietary semi-synthetic method) contains ubiquitin-lysine at position 15. The nucleosome is the basic subunit of chromatin. The 147 bp 601 sequence, identified by Lowary and Widom [1], has high affinity for histone octamers and is useful for nucleosome assembly. The DNA contains a 5’ biotin-TEG group.

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Product Options

Product Number Description Package Size List Price (CAD)
EP160399 Nucleosome, Recombinant Human, H2AK15ub1 dNuc, Biotinylated 25 µg
CA$861.00
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