Hycult Biotech

EndoCab® IgA, Human, ELISA Kit

Product Description

  • The EndoCab® IgA ELISA has been developed for determination of endotoxin core_x000D_ antibodies in human plasma or serum in patients or healthy individuals. Several studies show_x000D_ a consistent drop in postoperative levels of circulating anti-endotoxin core antibodies_x000D_
  • compared to the preoperative value. This drop has been interpreted as consumption of_x000D_ antibodies to endotoxin by systemic release of endotoxin. A hypothesis is that if the patients_x000D_ pre-operative endotoxin-core level is low, even moderately low, patients may not be able to_x000D_ cope with the efflux of endotoxin, which may have mild to severe clinical consequences. The_x000D_ assay is of interest for various experimental conditions ranging from in vitro LPS neutralization by plasma components to in vivo studies on kinetics of antibodies to endotoxin_x000D_ in health and diseases._x000D_
  • The EndoCab® standard median-units IgA (MU) are arbitrary and are based on medians of ranges for 1000 healthy adults in a particular locality. It has not been established whether_x000D_ normal endotoxin-core antibody values vary by region, culture or race. Users should_x000D_
  • establish appropriate local statistical controls for their studies. It is advised that studies of any_x000D_ patient group should always be controled by studies of appropriately selected contrasting_x000D_ clinical groups and/or healthy individuals recruited locally._x000D_ EndoCab® is a registered trademark. Used under license from the Scottish National Blood Transfusion_x000D_Service.
  • The EndoCab® IgA ELISA kit is to be used for the in vitro quantitative determination of endotoxin-core antibodies in serum, plasma and cell culture supernatant.

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Product Number Description Package Size List Price (CAD)
HYBHK504IGA EndoCab® IgA, Human, ELISA kit 1 x 96 det.
CA$1,329.00
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