IL-6, Mouse, Monoclonal Antibody MP5-32C11
- Supplier: Hycult Biotech
Product Description
- The antibody neutralizes mouse interleukin 6 (IL-6). It does not cross-react with LPS (the component of the_x000D_ bacterial cell wall which is considered responsible for the toxicity of gram-negative bacteria) and TNFalpha nor does it block human or rat IL-6 in proliferation assays using the KD83 cell line. MP5-32C11_x000D_ inhibits mouse IL-6-induced proliferation of the NFunctional Studies60 myelomonocytic cell line and KD83 plasmacytoma. IL-6 is a pluripotent 20-22 kDa cytokine which plays a role in the pathophysiology of severe infection and_x000D_
- regulates the immune response, acute phase reaction and haematopoiesis. IL-6 plays a critical role in Bcell_x000D_ differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma._x000D_ Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma_x000D_ cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibody producing_x000D_ hybridomas.
- Applications: Functional Studies , Immunoassays , Immunoprecipitation , Western Blot
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Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM1005100UG | IL-6, Mouse, mAb MP5-32C11, 100 µg | 100 µg |
CA$444.00
|
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