TIM-4, Mouse, Monoclonal Antibody Kat5-18
- Supplier: Hycult Biotech
Product Description
- The monoclonal antibody Kat5-18 recognizes T-cell immunoglobulin and mucin domain containing molecule (TIMD-4, also called TIM-4). TIMD-4 is a type I transmembrane protein belonging to the immunoglobulin superfamily, containing one Ig-like V-type (immunoglobulin-like) domain. TIMD-4 is expressed in Mac1+ cells in spleen, lymph nodes and fetal liver. TIMD-4 binds apoptotic cells by recognizing phosphatidylserine via its immunoglobulin domain. TIMD-4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIMD-4 is involved in regulating T-cell proliferation and lymphotoxin signaling. TIMD-4 and TIMD-1 are phosphatidylserine receptors for the engulfment of apoptotic cells, and are also involved in intracellular signaling in which exosomes are involved. The monoclonal antibody Kat5-18 blocks the engulfment of apoptotic cells by thymic macrophages.
- Applications: Flow Cytometry , Functional Studies , Immunoassays , Immunofluorescence
Resources
Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM111120UG | TIM-4, Mouse, mAb Kat5-18, 20 µg | 20 µg |
CA$235.00
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| HYBHM1111100UG | TIM-4, Mouse, mAb Kat5-18, 100 µg | 100 µg |
CA$430.00
|
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| HYBHM1111500UG | TIM-4, Mouse, mAb Kat5-18, 500 µg | 500 µg |
CA$1,850.00
|
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