Hycult Biotech

TIM-4, Mouse, Monoclonal Antibody Kat5-18, FITC

Product Description

  • The monoclonal antibody Kat5-18 recognizes T-cell immunoglobulin and mucin domain containing molecule (TIMD-4, also called TIM-4). TIMD-4 is a type I transmembrane protein belonging to the immunoglobulin superfamily, containing one Ig-like V-type (immunoglobulin-like) domain. TIMD-4 is expressed in Mac1+ cells in spleen, lymph nodes and fetal liver. TIMD-4 binds apoptotic cells by recognizing phosphatidylserine via its immunoglobulin domain. TIMD-4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIMD-4 is involved in regulating T-cell proliferation and lymphotoxin signaling. TIMD-4 and TIMD-1 are phosphatidylserine receptors for the engulfment of apoptotic cells, and are also involved in intracellular signaling in which exosomes are involved. The monoclonal antibody Kat5-18 blocks the engulfment of apoptotic cells by thymic macrophages.
  • Applications: Flow Cytometry , Functional Studies , Immunoassays , Immunofluorescence

Resources

Product Options

Product Number Description Package Size List Price (CAD)
HYBHM1111F20UG TIM-4, Mouse, mAb Kat5-18, FITC, 20 µg 20 µg
CA$242.30
Add to Cart
HYBHM1111F100UG TIM-4, Mouse, mAb Kat5-18, FITC, 100 µg 100 µg
CA$558.00
Add to Cart

List Prices are displayed.

Please register or log-in to the site to view your organization’s prices, or please add the products to your cart and click the “Request a Quote” button to receive price and availability information (include quantities for each product and indicate either a one-time purchase or your annual usage.)