CD46, Mouse, Monoclonal Antibody MM10
- Supplier: Hycult Biotech
Product Description
- The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46. MCP is a type I membrane glycoprotein that consists of four isoforms i.e. two C-isoforms (51-58 kDa) and two BC isoforms (59-68 kDa) which arise by alternative splicing of a single CD46 gene. Membrane cofactor protein is expressed on every cell and tissue, with the exception of erythrocytes. Membrane cofactor protein serves to down-regulate the activation of complement on host tissue. MCP is a cofactor for factor 1-mediated cleavage of C3b and C4b and this way serves to protect the host cell against autologous attack. MCP is a receptor for several pathogens including measles virus, group A Streptococcus pyogenes and pathogenic Neisseria.
- Applications: Frozen sections, Flow Cytometry , Immunoassays , Immunofluorescence , Western Blot
Resources
Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM111820UG | CD46, Mouse, mAb MM10, 20 µg | 20 µg |
CA$242.30
|
Add to Cart | |
| HYBHM1118100UG | CD46, Mouse, mAb MM10, 100 µg | 100 µg |
CA$666.00
|
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