IP-10, Human, Monoclonal Antibody 6D4
- Supplier: Hycult Biotech
Product Description
- The monoclonal antibody 6D4 recognizes human C-X-C motif chemokine 10 (IP-10), a protein of 98 amino acids. IP-10, also known as CXCL10, functions as ligand for the CXCR3 receptor. IP-10 belongs to the α-chemokine (C-X-C) family, which can be divided in two subfamilies: (1) potent chemoattractants for neutrophils, like IL-8 and (2) potent chemoattractants for lymphocytes, like the IFNɣ inducible protein (IP)-10. IP-10 is produced by a wide variety of cell types ranging from neutrophils, dendritic cells and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV, encephalitis, cutaneous T cell lymphoma, chronic hepatitis, psoriasis and acute anterior uveitis. Various observations strongly suggest a role for the C-X-C chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. Furthermore IP-10 is associated with acute rejection processes estimated by the predictive properties of urinary IP-10 expression for the short- and long-term graft function after kidney transplantation.
- Applications: Frozen sections, Flow Cytometry , Immunoassays , Immunofluorescence , Western Blot
Resources
Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM203020UG | IP-10, Human, mAb 6D4, 20 µg | 20 µg |
CA$242.30
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| HYBHM2030100UG | IP-10, Human, mAb 6D4, 100 µg | 100 µg |
CA$444.00
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| HYBHM203010MG | IP-10, Human, mAb 6D4, 10 mg | 10 mg |
CA$13,625.00
|
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| HYBHM20301MG | IP-10, Human, mAb 6D4, 1 mg | 1 mg |
CA$2,725.00
|
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| HYBHM2030500UG | IP-10, Human, mAb 6D4, 500 µg | 500 µg |
CA$1,912.00
|
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| HYBHM20305MG | IP-10, Human, mAb 6D4, 5 mg | 5 mg |
CA$10,215.00
|
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