MBL, Human, Monoclonal Antibody 3E7, FITC
- Supplier: Hycult Biotech
Product Description
- Mannose Binding Lectin (MBL) also called mannose- or mannan-binding protein (MBP) is a member of the group of collectins. MBL is an oligomeric lectin that recognizes carbohydrates as mannose and N-acetylglucosamine on pathogens. MBL contains a cysteine rich, a collagen like and a carbohydrate recognition domain. It forms a complex with C1r/C1s like serine proteases designated MASPs that proteolytically cleave C4, C2 and C3. MBL is able to activate the complement pathway independent of the classical and alternative complement activation pathways. The MBL-MASP pathway (better known as the lectin pathway) is antibody and C1q-independent. MBL exhibits complement-dependent antibacterial activity and acts directly as an opsonic and therefore plays an important role in innate immunity. MBL is synthesized by hepatocytes and has been isolated from the liver or serum of various vertebrate species.
- Applications: Frozen sections, Flow Cytometry , Immunoassays , Western Blot
Resources
Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM2061F20UG | MBL, Human, mAb 3E7, FITC, 20 µg | 20 µg |
CA$235.00
|
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| HYBHM2061F100UG | MBL, Human, mAb 3E7, FITC, 100 µg | 100 µg |
CA$986.00
|
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