Ficolin-2, Human, Monoclonal Antibody GN5
- Supplier: Hycult Biotech
Product Description
- The monoclonal antibody GN5 recognizes human Ficolin-2, also known as L-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed by monocytes, granulocytes and lung cells and is present locally in areas of inflammation._x000D_
- Ficolin-2 (also L-ficolin, ficolin L, EBP-37 or hucolin) is produced primarily by the liver. The association between Ficolin-2 and MASPs/sMAP is Ca2+-dependent. MASPs in Ficolin-2-MASP complexes have proteolytic activities for C4, C2 and C3. Ficolin-2 also shows opsonic activity._x000D_
- Applications: Immunoassays , Immunoprecipitation , Western Blot
Resources
Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM209120UG | Ficolin-2, Human, mAb GN5, 20 µg | 20 µg |
CA$235.00
|
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| HYBHM2091100UG | Ficolin-2, Human, mAb GN5, 100 µg | 100 µg |
CA$880.00
|
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| HYBHM2091500UG | Ficolin-2, Human, mAb GN5, 500 µg | 500 µg |
CA$1,850.00
|
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