Hycult Biotech

Ficolin-2, Human, Monoclonal Antibody GN5

Product Description

  • The monoclonal antibody GN5 recognizes human Ficolin-2, also known as L-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed by monocytes, granulocytes and lung cells and is present locally in areas of inflammation._x000D_
  • Ficolin-2 (also L-ficolin, ficolin L, EBP-37 or hucolin) is produced primarily by the liver. The association between Ficolin-2 and MASPs/sMAP is Ca2+-dependent. MASPs in Ficolin-2-MASP complexes have proteolytic activities for C4, C2 and C3. Ficolin-2 also shows opsonic activity._x000D_
  • Applications: Immunoassays , Immunoprecipitation , Western Blot

Resources

Product Options

Product Number Description Package Size List Price (CAD)
HYBHM209120UG Ficolin-2, Human, mAb GN5, 20 µg 20 µg
CA$242.30
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HYBHM2091100UG Ficolin-2, Human, mAb GN5, 100 µg 100 µg
CA$909.00
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HYBHM2091500UG Ficolin-2, Human, mAb GN5, 500 µg 500 µg
CA$1,912.00
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