Beta-Catenin, Human, Monoclonal Antibody 9F2
- Supplier: Hycult Biotech
Product Description
- Beta-catenin belongs together with alpha- and gamma-catenin to the catenin family. Catenins mediates cell-cell adhesion by interaction with cadherins. Beta-catenin is highly homologous to gamma-catenin (plakoglobin) although its function differs from that of plakoglobin. Whereas plakoglobin has been found to suppress tumorigenicity, beta-catenin potentiates hyperproliferation and tumor formation. In the nucleus beta-catenin it complexes with transcription factors and thus regulates the expression of specific genes. By its dual role, i.e. a structural role in cell-cell junctions and a regulatory role in the nucleus, beta-catenin can transduce changes in cell adhesion and junction formation to control transmembrane signalling and gene expression.
- Applications: Flow Cytometry , Immunofluorescence , Immunoprecipitation , Western Blot
Resources
Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM211220UG | Beta-Catenin, Human, mAb 9F2, 20 µg | 20 µg |
CA$235.00
|
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| HYBHM2112100UG | Beta-Catenin, Human, mAb 9F2, 100 µg | 100 µg |
CA$644.00
|
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