Desmoglein-3, Human, Monoclonal Antibody 5G11
- Supplier: Hycult Biotech
Product Description
- Desmoglein 3 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 3 is synthesized in both the basal and the lower suprabasal compartments. The monoclonal antibody 5G11 reacts with the 140 kDa desmoglein 3 protein. Furthermore it is not cross reactive with desmoglein 1 or desmoglein 2.
- Applications: Immunofluorescence , Immunoprecipitation , Paraffin sections , Western Blot
Resources
Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM211520UG | Desmoglein-3, Human, mAb 5G11, 20 µg | 20 µg |
CA$235.00
|
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| HYBHM2115100UG | Desmoglein-3, Human, mAb 5G11, 100 µg | 100 µg |
CA$644.00
|
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