CD11b, Human, Monoclonal Antibody Bear-1
- Supplier: Hycult Biotech
Product Description
- CD11b is an alpha chain integrin that is expressed as heterodimer noncovalently associated with CD18. CD11b is also designated as CR3, Mac-1, Mo-1 in integrin alphaM subunit and has a molecular weight of 165-170 kDa. The protein mediates PMN and monocytes adherence to endothelium and subsequently PMN extravasation to sites of inflammation. CD11b/CD18 interacts with both matrix and cell surface proteins including the complement component iC3b, extracellular matrix proteins and the third extracellular domain of CD54. CD11b is expressed on human NK-cells, monocytes, granulocytes, T-cells, B-cells and dendritic cells. After activation the expression is upregulated. Bear-1 reacts with the CD11b alpha chain of the CD11b/CD18 (p165, 95) integrin heterodimer complex.
- Applications: Frozen sections, Flow Cytometry , Immunoprecipitation
Resources
Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM212520UG | CD11b, Human, mAb Bear-1, 20 µg | 20 µg |
CA$242.30
|
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| HYBHM2125100UG | CD11b, Human, mAb Bear-1, 100 µg | 100 µg |
CA$666.00
|
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