C5, Human, mAb 10B6
- Supplier: Hycult Biotech
- Storage Conditions: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least six months.
Product Description
- The complement system plays important roles in both innate and adaptive immune response and can produce an inflammatory and protective reaction to challenges from pathogens.
- Complement C5 is a central molecule in all three pathways and after cleavage by its convertases, it initiates the terminal pathway in order to generate the cytolytic MAC.C5 is mainly synthesised in the liver as a single polypeptide chain and is present in serum in a concentration of 50-80 μm/ml. Besides, local synthesis of C5 is also supported by other cell types including monocytes/macrophages, neutrophils, fibroblasts, and astrocytes. Before secretion the molecule is glycosylated and secreted into plasma as a 190 kDa glycoprotein consisting of a disulphide linked alpha-chain (111 kDa) and beta-chain (75 kDa).
Resources
Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM2414100UG | C5, Human, mAb 10B6, 100 µg | 100 µg |
CA$794.00
|
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| HYBHM241410MG | C5, Human, mAb 10B6, 10 mg | 10 mg |
CA$13,188.00
|
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| HYBHM24141MG | C5, Human, mAb 10B6, 1 mg | 1 mg |
CA$2,638.00
|
Add to Cart | |
| HYBHM241420UG | C5, Human, mAb 10B6, 20 µg | 20 µg |
CA$235.00
|
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| HYBHM2414500UG | C5, Human, mAb 10B6, 500 µg | 500 µg |
CA$1,850.00
|
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| HYBHM24145MG | C5, Human, mAb 10B6, 5 mg | 5 mg |
CA$9,887.00
|
Add to Cart |
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