Ethenoadenosine, Monoclonal Antibody 1G4
- Supplier: Hycult Biotech
Product Description
- The reaction of chloroacetaldehyde (CAA) with DNA results in the formation of ethenoadenosine also known as 1,N6-ethenodeoxy-adenosine or etheno-A. CAA is formed through metabolization of for example vinyl chloride, a well established carcinogen. In RNA, after in vitro activation, etheno-A and etheno-C are the principle products of RNA damage. Etheno derivate formation may be highest in single-stranded DNA-regions. The monoclonal antibody 1G4 reacts with both the ribose and deoxyribose form of the adduct. The antibody is not cross reactive with non-modified DNA or the normal nucleotides.
- Applications: Frozen sections, Flow Cytometry , Immunoassays , Immunoprecipitation , Western Blot
Resources
Product Options
Product Number | Description | Package Size | List Price (CAD) | ||
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HYBHM500520UG | Ethenoadenosine, mAb 1G4, 20 µg | 20 µg |
CA$242.30
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HYBHM5005100UG | Ethenoadenosine, mAb 1G4, 100 µg | 100 µg |
CA$821.00
|
Add to Cart |
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