Hycult Biotech

Ethenoadenosine, Monoclonal Antibody 1G4

Product Description

  • The reaction of chloroacetaldehyde (CAA) with DNA results in the formation of ethenoadenosine also known as 1,N6-ethenodeoxy-adenosine or etheno-A. CAA is formed through metabolization of for example vinyl chloride, a well established carcinogen. In RNA, after in vitro activation, etheno-A and etheno-C are the principle products of RNA damage. Etheno derivate formation may be highest in single-stranded DNA-regions. The monoclonal antibody 1G4 reacts with both the ribose and deoxyribose form of the adduct. The antibody is not cross reactive with non-modified DNA or the normal nucleotides.
  • Applications: Frozen sections, Flow Cytometry , Immunoassays , Immunoprecipitation , Western Blot

Resources

Product Options

Product Number Description Package Size List Price (CAD)
HYBHM500520UG Ethenoadenosine, mAb 1G4, 20 µg 20 µg
CA$242.30
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HYBHM5005100UG Ethenoadenosine, mAb 1G4, 100 µg 100 µg
CA$821.00
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