BPDE-DNA, Monoclonal Antibody 5D11
- Supplier: Hycult Biotech
Product Description
- A number of chemicals, including polycyclic aromatic hydrocarbons (PAHs), have been shown to bind to DNA. This DNA damage can occur both early and late in the malignant process, thereby acting as an initiator and assisting in the progression of tumors. PAHs are released into the environment following incomplete combustion of organic materials. The most common sources of PAHs are from smoking and from consuming broiled or grilled foods. Human exposure to PAHs comes from various occupational, environmental, dietary and medicinal sources. Benzo[a]pyrene is a representative PAH. Antibodies to benzo[a]pyrenediol-epoxide modified DNA (BPDE-DNA) can be used to identify polycyclic aromatic hydrocarbon (PAH)-DNA adducts. Exposure to this group of compounds is believed to be carcinogenic. The monoclonal antibody 5D11 recognizes BPDE-I-DNA (PAH-DNA).
- Applications: Flow Cytometry , Immunoassays , Immunofluorescence , Immunoprecipitation , Paraffin Sections
Resources
Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM500720UG | BPDE-DNA, mAb 5D11, 20 µg | 20 µg |
CA$242.30
|
Add to Cart | |
| HYBHM5007100UG | BPDE-DNA, mAb 5D11, 100 µg | 100 µg |
CA$909.00
|
Add to Cart |
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