IL-1RII, Human, Polyclonal Antibody
- Supplier: Hycult Biotech
Product Description
- The antibody reacts specificly with human Interleukin (IL-1)RII. The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1RI and IL-1RII) and the IL-1 receptor accessory protein. The IL-1RII is part of the antagonistic IL-1 mechanism. It is also known as decoy receptor and is a non signalling molecule which functions by capturing IL-1 and preventing it from interacting with the signalling IL-1RI. The decoy IL-1RII can after binding to IL-1 also recruit the IL-1 receptor accessory protein and thus inhibit by coreceptor competition. Further a soluble form of IL-1RII exists which is shed, a process in which matrix metalloproteases have been found to play a role, by various cells including monocytes, polymorphonuclear cells, B cells and fibroblasts.
- Applications: Immunoassays
Resources
Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHP900720UG | IL-1RII, Human, pAb, 20 µg | 20 µg |
CA$235.00
|
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| HYBHP9007100UG | IL-1RII, Human, pAb, 100 µg | 100 µg |
CA$644.00
|
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