Cell Guidance Systems

5-Azacytidine

Product Description

  • 5-Azacytidine is an epigenetic modifier, a potent growth inhibitor and a cytotoxic agent.
  • It acts as a demethylating agent by inhibiting DNA methyltransferase (DNMT), forming covalent adducts with cellular DNMT1 depleting enzyme activity. This small molecule enhances differentiation to cardiomyocytes from human embryonic stem cells.
  • 5-Azacytidine also increases reprogramming efficiency of mouse fibroblasts to pluripotent stem cells.

Resources

Product Options

Product Number Description Package Size List Price (CAD)
CGSM07200 5-Azacytidine 200 mg
CA$253.90
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CGSM0750 5-Azacytidine 50 mg
CA$100.20
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