Vector Laboratories

GNL, Agarose

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Product Description

  • Galanthus Nivalis Lectin (GNL), Agarose bound, 5 ml. This product is prepared using Vector Laboratories affinity-purified lectins. GNL is not a metalloprotein and does not require Ca++ or Mn++ for binding. Binding seems to be directed toward structures containing (alpha-1,3) mannose residues but not alpha-linked glucose. This lectin reportedly binds rat and mouse IgM (not IgG), alpha2-macroglobulin from human serum, and many viral glycoproteins. Bead diameter 45–165 μm. Matrix is stable in solutions at pH 3–11 and in many organic solvents. Prepared using affinity-purified lectins. Covalent attachment preserves lectin activity. Hydrophilic spacer arm separates the lectin and matrix. Conjugated proteins do not leach off beads with buffers. No residual charges present after conjugation, minimizing non-specific binding. Product is a 1:1 suspension in buffer, 3 mg lectin/ml gel. Inhibiting/Eluting Sugar: 100–200 mM alpha-methylmannoside or Glycoprotein Eluting Solution (Cat. No. ES-1100).

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Product Number Description Package Size List Price (CAD)
VECTAL12435 Galanthus Nivalis Lectin (GNL), Agarose bound, 5 ml 5 mL
CA$792.00
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