May 2017
Dear Researcher,
We are pleased to present the e-Lynx, a newsletter devoted to keeping our customers up-to-date on new technologies, our new products, suppliers, activities and promotions.
- New Products
- New Literature
- Promotions
- Technical Report
- Announcements
- Events
- MJSBioLynx Well Being
NEW PRODUCTS
Vector Laboratories – Cyanine Dye Conjugated Lectins
- More robust and intense fluorescence compared with Vector’s existing traditional fluorophore conjugates
- Intended to be used to identify glycoprotein expression on cells and tissue sections
- Applications therefore include immunofluorescence and flow cytometry
Click here to order or request a quote.
Image: Colon (FFPE): Antigen retrieved with Antigen Unmasking Solution, stained with Cy5 Sambucus Nigra Lectin (SNA; fuchsia). DAPI counterstain (blue).
Micronic – TPE Push Caps RB
In addition to the current TPE Push Caps, which are manufactured from Medical approved material (USP Class VI certificate), Micronic now launches the TPE Push Caps RB in a Capcluster-96 and Capband-8 format. Since the raw material used for the TPE Push Caps RB does not have to meet the medical grade standards, this product is a highly cost effective solution for most research applications. These caps are currently only available in 'Natural'.
Manufactured and assembled in a certified Class 7 Clean Room- RNase/DNase/Pyrogen free
- Reliable delivery times
- Superior sealing down to -80°C
- Minimal evaporation
- Compatible with manual and electric Push Cap equipment
Click here to order or request a quote.
NuGEN - Universal Plus mRNA-Seq
Universal Plus mRNA-Seq is a comprehensive solution for mRNA sequencing with the unique option to eliminate unwanted transcripts from the library.
- Broad dynamic input range from 1 ug to as low as 10 ng, enables access to previously inaccessible low input samples
- Efficient library construction with minimal adaptor dimers enabled by proprietary DimerFree technology
- Customizable transcript depletion with AnyDeplete maximizes informative data from mRNA sequencing
Click here for more information.
Click here to order or request a quote.
NuGEN – Trio RNA-Seq
Trio RNA-Seq provides a highly sensitive whole transcriptomics solution that is ideally suited for applications with low abundance transcripts, such as detection of viral transcripts or biomarker assessment in liquid biopsy samples.
- Consistent performance from wide input range - High quality data from as low as 500 pg
- Unbiased transcript coverage
- Excellent results from FFPE and/or degraded samples
Click here for more information.
Click here to order or request a quote.
Hycult Biotech – Pig Complement Pathway Assays
The Pig Classical and Lectin Complement Pathway ELISAs are easy-to-use and specific per pathway by making use of a combination of specialized coatings and buffers. Complement deficiencies or other defects in the complement system can easily be screened by running an assay for each pathway in parallel or separately. The pig platform is ideal for use as a model for transplantation research.
- Classical Complement Pathway
- Lectin Complement Pathway
Click here to order or request a quote.
Jena Bioscience - Linker-optimized Cy3- and Cy5-modified dUTPs
Labeling of DNA probes for in situ hybridization is most often performed by enzymatic incorporation of labeled dUTP using Taq DNA polymerase. The new linker-optimized Cy3- and Cy5-modified dUTPs possess a longer linker resulting in higher labeling efficiencies at similar substitution rates.
- Recommended for direct enzymatic labeling of DNA/cDNA e.g. by PCR and Nick Translation
- Incorporated as substitute for its natural counterpart dTTP
- The resulting Dye-labeled DNA/cDNA probes are ideally suited for fluorescence hybridization applications such as FISH or microarray-based gene expression profiling
Click here for more information (Link to Jena Bioscience website)
Click here to order or request a quote.
NEW LITERATURE
Vector Laboratories – Immunohistochemistry Guide
Selecting the appropriate reagents for your IHC assay is an important part of optimizing your protocol. This IHC Resource Guide will help you navigate through the many choices of detection systems, substrates, and ancillary reagents that complete your workflow. Click here to download.
Contact our Customer Service Team to request printed copies of this publication,
e-mail sales@biolynx.ca or call 1-888-593-5969.
Matreya – April 2017 Newsletter for Glyco/Sphingolipid Research
This issue features Functions of the Neuronal Lipid Trisialoganglioside GT1b, Sphingomyelin and Sphingosylphosphorylcholine: Vital Membrane Components, and Novel Adamantane Labeled Sphingolipids. Click here to download.
PROMOTIONS
MJSBioLynx - Clearance Sale
Take advantage of great low prices on quality Life Science research products.
Hurry while quantities last!
This sale includes:
|
|
Click here to order.
Clearance prices are valid for items in stock only, while quantities last.
Cannot be combined with other offers or discounts.
Micronic – FREE Tubes with Purchase of a Screw Cap Recappers
The Recapper SR096 caps or decaps 96 screw cap tubes at once in less than 30 seconds. The Recapper SR008 handheld device offers users the ability to cap, decap or recap a row of 8 tubes in less than 5 seconds! These systems minimize sample evaporation, significantly improve productivity, and ensure each screw cap is tightened securely and uniformly.
Get a Univo Screw Cap Recapper SR096
with 40 racks of precapped tubes in your choice of rack for FREE.
Click here to order.
Get a Univo Screw Cap Recapper SR008
with 10 racks of precapped tubes in your choice of rack for FREE.
Click here to order.
Offers valid until June 30th, 2017.
Cannot be combined with other offers or discounts.
Micronic – FREE Tissue Tubes with Purchase of a Tracxer Code Reader RS210
The Tracxer Code Reader RS210 is a small bench top rack scanner that can read 2D codes quickly and cost effectively within 5 seconds. The compact reader is built for high throughput and automated systems.
Get a Tracxer Code Reader RS210
with 10 racks of 3.00mL Tissue Tubes for FREE
Click here to order.
Offer valid until June 30th, 2017.
Cannot be combined with other offers or discounts.
HumanZyme - Up to 25% OFF HumanKine® and 10% OFF XKine™ Proteins
Save 25% OFF HumanKine® Human Expressed Proteins
- Authentic human proteins
- Animal-free and xeno-free
- High bioactivity and improved half-life due to natural glycosylation
and native hetero-dimer formation (versus murine, CHO and E. coli) - Validated in over 200 citations
- Easily adaptable to cGMP grade
Click here to order.
- Save 10% OFF the New HumanKine® Wnt-3a
- HEK293-expressed
- Animal-derived product free
- High Activity
- Lyophilized and Carrier Free (CF)
Click here to order.
- Save 10% OFF XKine™ Proteins
- Human recombinant proteins that are expressed in E. coli, insect, CHO and other mammalian cell lines.
- Economical prices
Click here to order.
Offers valid until June 30th, 2017
Promotion Code HUZ0417
Cannot be combined with other offers or discounts.
25% discount not applicable to HumanKine® Wnt-3a Protein which is available at a 10% discount.
Enzo Life Sciences – Save 20% OFF Interleukin ELISA Kits
Save on Enzo Life Sciences’ easy-to-use ELISA kits for human and mouse interleukins. Each assay is put through rigorous testing to ensure high precision, accuracy, sensitivity, and specificity. You can be confident that you will obtain reproducible results, day-after day and lot-after-lot.
Click here to order or request a quote.
Offer valid until July 31, 2017.
Please reference Promotion Code ELISA20IL.
Cannot be combined with other offers or discounts.
Click here
|
TECHNICAL REPORT
Hycult Biotech – NETs are Associated with Inflammation in Asthma and COPD
Summary of Wright, T et al; Neutrophil extracellular traps are associated with inflammation in chronic airway disease. Respirology, April 2016. Click here for the full article.
Neutrophil extracellular traps (NETs) are created when neutrophils release granule proteins, histones and chromatin to form extracellular matrices. They represent an important strategy to immobilize and kill invading microorganisms, yet their role in respiratory disease remains unclear.
This study aimed to investigate the presence of NETs in sputum from patients with asthma and COPD, and the relationship of NETs with inflammatory phenotype and disease severity. Sputum of 44 COPD patients, 94 asthma patients and 27 healthy controls was collected and used to quantify granular proteins (α-defensins 1-3 and LL-37), gene expression and extracellular DNA. Results of the study indicate that eDNA and antimicrobial proteins accumulate in the airways in asthma and COPD. The paper further concludes that NETs and NET components are elevated in severe neutrophilic asthma and COPD, and are associated with other markers of activated innate immune responses.
ANNOUNCEMENTS
We are pleased to announce the addition of 2 new Technical Sales Representatives to our team
Kevin Coll in Toronto
Kevin received his B.Sc. in Biological Science from the University of Guelph in 2013. He also minored in Zoology and Business Administration. While at Guelph, Kevin was involved in a number of volunteer positions, including organizing a local soccer league, establishing a student-run club, the Biomimicry Collaboration, as well as working as a Research Assistant in multiple labs. After graduation, Kevin worked as a scientific officer for a research-based not-for-profit organization called FRAME (the Fund for the Replacement of Animals in Medical Experiments) in England. His focus was to research viable alternatives to the use of animals in experimental procedures that provided comparable or better results.
Lance Brazeau in South Western Ontario
Lance received his B.E.Sc in Chemical Engineering from Western University in London in 2016. He specialized in Biochemical and Environmental processes with a background in tissue engineering, bio-separation processes and bio reaction engineering. He joined MJSBioLynx as a Technical Support Specialist before transitioning into his new role as a Technical Sales Representative.
Kevin and Lance will be able to visit you at your convenience to discuss your product needs and quotes. They can both be reached through our Brockville office Toll Free at 1-888-593-5969 or via email at kevinc@sales.biolynx.ca and lanceb@biolynx.ca.
Kevin and Lance look forward to meeting you and continuing the high level of personal service associated with MJSBioLynx.
EVENTS
Visit us at the following event:
The Third Conference of the Canadian Society for Chronobiology
May 19th-21st, 2017
York University, Toronto, ON
www.chronobiocanada.com
MJSBioLynx WELL BEING
5 Unexpected Ways Meditation Can Help Your Career
By Gina Belli, PayScale
"Too often, our working lives are typified by long days, late-night emails, and unused vacation time. But, more and more, we’re beginning to understand the positive impact of wellness and mindfulness practices."
It’s good for your health- It improves cognitive function
- It supports happiness, decision-making, and time-management goals
- It helps us tap into our intuition and wisdom on a deeper level
- It supports flow state, creativity, and innovation
Click here to read more. (Link to Business Insider Website)
Click here to visit the MJSBioLynx Well Being website