Biorbyt – Cancer Biomarkers

Biorbyt offers specialized tools for some of the most researched oncology biomarkers. These products facilitate a deeper understanding of cancer pathways, helping to drive discoveries in diagnostics and therapeutic targets.

By equipping scientists with tools tailored for oncology research, Biorbyt aims to empower innovations that bring us closer to effective cancer diagnostics and treatments.

Product Categories
Biorbyt products are crafted for various applications, including detection, quantification, and functional assays. Each product is optimized to streamline cancer research processes and help you achieve high-quality, consistent data.

BioEcho Life Sciences – EchoLUTION™

Goodby Silica...Hello EchoLUTION^™
Even the most routine molecular biology protocols can be improved.

While the world of nucleic acid analysis increased exponentially, the one of nucleic acid extraction stayed still for more than 40 years. At BioEcho, they search for novel ideas and question conventional routine methods to foster innovation. 

Their principal focus was to develop products able to extract high-quality DNA and RNA more easily, quickly, and sustainably. That was when their EchoLUTION^™ technology – based on a single-step purification method – was born.

Forget About Binding

Why bind your DNA and RNA to a silica membrane or bead when you could allow it to flow through freely – saving you steps and time? The EchoLUTION technology purifies nucleic acid in a single step, avoiding unnecessary interactions with organic solvents like ethanol.

Banish Washing Steps

Why expose your nucleic acids to nonessential centrifugation steps that could lead to fragmentation? Improve your nucleic acid extraction using the EchoLUTION single-step centrifugation method, and forget about wasting your DNA and RNA. With this technology, you will not only reduce the hands-on steps but also the overall hands-on time, allowing you to achieve your results faster.

Ditch the Unnecessary

Why not extract your DNA and RNA with a user and environmentally-friendly product? Boost your nucleic acid extraction with the revolutionary single-step EchoLUTION technology and obtain high-quality DNA and RNA faster and with minimal environmental impact. BioEcho's workflow and product reduce plastic consumables and use fewer hazardous reagents. Extracting DNA and RNA can now be greener!

Vector Laboratories – VECTASTAIN® Elite® ABC-HRP Kit, Peroxidase (Standard)

The VECTASTAIN Elite ABC system is the most sensitive avidin/biotin-based peroxidase system and is approximately 5 times more sensitive than the original VECTASTAIN ABC Kit. It is available without a biotinylated secondary antibody (Standard kit).

Features:

• Advanced avidin/biotin technology: The Elite ABC complex is smaller, very uniform,
  and highly active, allowing more accessibility for binding to a biotinylated target.
• Cost effective: Higher sensitivity leads to lower cost per slide.
• Kit contains sufficient reagents to stain approximately 500-1000 sections.

Solis BioDyne – SolisFAST® Master Mix, Ready to Load

SolisFAST^® Master Mix is a 5x-concentrated, ready-to-use solution for fast singleplex and multiplex endpoint PCR assays. The mix allows amplification of up to 5 kb fragments from low complexity DNA templates (e.g. lambda, plasmid DNA), and up to 3 kb from complex DNA templates (e.g. human genomic DNA).

• PCR Results in 20 minutes
• Analyze one or multiple targets per reaction
• Load directly on gel after PCR
• Ice-free shipping
•   Reduces lab waste

USA Scientific – Vortex Mixer

• 2-in-1 Convenience – Mix and vortex in one compact device.
• Precise Speed and Duration Control – Use the digital presets for quick vortexing or customize for precise mixing.
• Glove Compatible Touchscreen – Keep gloves on while programming.
• Quick Touch Mode – Press the tube to the standard attachment for quick gentle mixing to vigorous vortexing.

For a limited time, purchase the Vortex Mixer and receive the tube adapter and microplate adapters at no charge.

Micronic – Rack Readers

Complete Range for Every Budget!

To enable fast, accurate and efficient sample identification, Micronic offers an extensive code reader range which consists of whole rack and single tube readers.

View all Code Reader Overviews & Specifications below.

Vector Laboratories – VECTASHIELD® Antifade Mounting Media & TrueVIEW® Autofluorescence Quenching Kits

If you love the Vector Laboratories’  VECTASHIELD Antifade Mounting Media - The MOST widely referenced antifade mounting media, then you may also love the TrueVIEW Autofluorescence Quenching Kits.

These kits provide a novel way to remove unwanted fluorescence in tissue sections due to aldehyde fixation,
red blood cells, and structural elements such as collagen and elastin.

TrueVIEW Quenching reagent is a unique approach to diminish unwanted autofluorescence from non-lipofuscin sources, that retains the specific fluorescent antigen staining. The quenching action of the kit reagents therefore, provides the investigator with a clear, unambiguous, “true view” visualization of the intended target.

You may also like the VectaPlex^™ Antibody Removal Kit. This ready-to-use kit is designed to remove antibodies and other non-covalently bound detection reagents from formalin-fixed paraffin-embedded (FFPE) tissue sections in immunofluorescence or tyramide signal amplification staining workflows.

VECTASHIELD Antifade Mounting Media		TrueVIEW Autofluorescence Quenching Kits		VectaPlex Antibody Removal System

Associates of Cape Cod, Inc. – PyroSmart NextGen® Recombinant Cascade Reagent (rCR)

News Flash! U.S. Pharmacopeia (USP) Microbiology Expert Committee to permit the use of non-animal-derived reagents for endotoxin testing.

With this announcement, pharmaceutical and medical device manufacturers can consider with confidence, integrating this new recombinant technology platform into their quality assurance processes.

Now's the time to find out how easy transitioning to PyroSmart NextGen^® is.

• No Animal Content – Horseshoe Crab Blood Free
• Same Cascade, Instrument & Preparation Steps
• No Cross Reactivity With 1,3-ß-D-Glucan

PyroSmart NextGen^® can be used for a wide variety of endotoxin tests, ranging from standard
water testing to samples requiring high sensitivity, such as intrathecal products and those
requiring high dilutions to overcome interference.

Mirus Bio – Discovery Research

Spend less time searching for a transfection reagent and more time moving your innovations forward.

Mirus Bio offer a range of effective transfection solutions and tools for a comprehensive set of cell lines. These solutions are intentionally designed to be gentle on cells and maximize cell delivery while using a simplified, straightforward protocol.

Discovery Research Applications

CRISPR/Cas Genome Editing
Stem Cell Transfection
RNAi Gene Silencing
mRNA and Viral RNA Transfection
Stable Cell Line Generation
Low Toxicity Transfection
Co-Transfection
Electroporation

Our Top Selling Transfection Reagent – TransIT^®-LT1 Transfection Reagent

• Broad Spectrum DNA Delivery – Utilize one transfection reagent and protocol for a variety of cells
• High Efficiency Delivery – Achieve expression in a large population of cells for experimental success
• Deliver Single or Multiple Plasmids – Suitable for applications such as virus production
• Request a Sample today!

TransIT^®-LT1 Full Transfection Protocol (PDF)

We’re here to help you find the right Transfection Reagent for your research – Canadians helping Canadians.

Vector Laboratories – Fluorescent Dyes

If you're working on cell analysis, imaging, bioconjugation, spatial biology, next gen sequencing, antibody development, pathology kits development or similar applications, Vector Laboratorieshave the Fluorescent Dyes for you!

Choose. Label. Publish. Get glowing results with the optimal fluorescent dye.

Check out their Dye Selector Tool & Selection Catalogue!

BioEcho Life Sciences – RNA/DNA Extraction

BioEcho is a specialized solution provider for the extraction and analysis of nucleic acids using spin column technology.  They create disruptive technologies, products, and workflows that make downstream processing of nucleic acids easier and faster.

Fast and Convenient – DNA and RNA extraction in one step, 50-70% faster than established methods.
High Sensitivity – Highly pure DNA/RNA free of contaminants and inhibitors.
Reliable Results – Lysis under physiological conditions results in long and intact DNA/RNA perfectly suited for downstream applications such as PCR, NGS, RT-PCR, RNA-seq, and more.
Sustainable – Reduces plastic consumption by up to 70% and minimizes use of hazardous reagents.

Available EcoLUTION^™ Products from BioEcho:
RNA Extraction: Cell Culture, Viral, FFPE, Tissue
DNA Extraction:  Blood, Buccal Swab, Cell Culture, FFPE, Plant, Tissue, Viral
Nucleic Acid Cleanup:  DNA Cleanup, DNA Organic Solvent Cleanup, RNA Cleanup Enzymes, Reagents and Accessories

Vector Laboratories – VectaPlex™ Antibody Removal Kit

This ready-to-use kit is designed to remove antibodies and other non-covalently bound detection reagents from formalin-fixed paraffin-embedded (FFPE) tissue sections in immunofluorescence or tyramide signal amplification staining workflows.

VectaPlex simplifies sample processing for manual workflows, accelerates multiplex assay optimization, preserves precious samples, and maintains tissue integrity and morphology through multiple cycles of antibody binding and removal.

Obtain more spatial biomarker information from each tissue section:

• Detect 7+ targets in a single tissue using two-color fluorescent imaging and standard IF reagents.
• Multiplex at room temperature with minimal tissue damage or loss of antigenicity.
• Preserve precious sample in IF and TSA, including sensitive tissues such as lung, skin, and breast.
• Stain with multiple primaries from the same species and a single secondary without cross-reactivity.
• Reduce the need for optimization of the sequence in which antibodies are bound during TSA.

Micronic – Sample Storage Tubes and Tube Wizard

Micronic offers a complete line of sample storage tubes that fit in the 96-well, 48-well or 24-well rack format. All Micronic sample storage tubes are manufactured to industry leading strict tolerances and are available non-coded, alphanumeric coded, or with a unique 2D Data-Matrix code on the tube bottom, which can be combined with a 1D barcode on the tube side.

• Medical approved virgin polypropylene
• Low protein binding surface
• Mechanical strength
• Pyrogen free
• Black or white code surface (bottom and/or side) cannot be separated from the transparent tube
• Permanent laser-etched code on the tube bottom, which is chemically, scratch and mechanically resistant

Mirus – A Legacy of Transfection Innovation

Mirus Bio receives ISO 13485:2016 certification, underscoring the quality of processes used
to support GMP product portfolio.

Mirus offers a range of effective transfection solutions and tools for a comprehensive set of cell lines.
These solutions are intentionally designed to be gentle on cells and maximize cell delivery while
using a simplified, straightforward protocol.

NEST Biotechnology – Cell Culture Labware

NEST Biotechnology is a worldwide manufacturer of plastic laboratory products. They offer a wide variety of consumables including cell culture labware, sample collection, centrifuge tubes, assay plates, PCR consumables, cryogenic tubes and much more!

Vector Laboratories – Lectins for Your Research!

Lectins are versatile tools in life science research, impacting fields such as molecular biology, immunology, medicine, and clinical analysis. Their ability to recognize glycans opens avenues for innovative discoveries and applications. In cancer research, they have proven to be a useful tool for the identification of novel PSA biomarkers and for gaining valuable insight into the glycan profile of a sample for the development of anticancer therapeutics.

For the months of April to July 2024, we are offering a discount on all lectins and bioconjugation products in support of cancer awareness month.

GlycoSelect – Highly Recombinant Prokaryotic Lectins

Highly Specific Recombinant Prokaryotic Lectins from GlycoSeLect has developed a range of RPL products exhibiting specificity and high affinity for a range of glycan epitopes displaying terminal galactose and mannose (including high mannose structures).

All RPL products display a poly-histidine tag enabling simple detection using standard conjugated anti-his detection antibodies negating a requirement for in vitro labeling (e.g. biotinylation).

Products are available in a range of pack sizes and can be supplied in large quantities (grams) if required.

For the months of April to July 2024, we are offering a discount on all lectins and bioconjugation products in support of cancer awareness month.

MicronPlus - Pattern Adhesive PTFE Sealing Films – No Heat Sealer Required!

MicronPlus pattern adhesive PTFE sealing films for microplates are specifically designed to eliminate clogging and contamination of needles and offer the best optical clarity for inspection and diagnostic applications.

• Adhesive-free well coverage
• Available with pre-slit feature in center of each well
• No cross-contamination or evaporation
• Outstanding resistance to solvents and extreme temperatures

Click here for more information.
Click here to order or request a quote.

NEST Biotechnology – ELISA, Deep Well, and PCR 96-Well Plates

ELISA Plates

Features:

• Plates present good adsorption performance and low baseline value.
• Uniform thickness and size.
• High batch-to-batch stability and low coefficient of variation (CV) value.
• Both detachable and non-detachable flat-bottom plates are offered for customers to choose from based on their applications.
• The letters and numbers on the frame of the plates are convenient for detection and identification in experiments.
• High transparency of clear plate bottom.
• White plates are best suited for luminescence measurements as they reflect the signal instead of absorbing it and hence enhance the luminescence signals.

Deep Well Plates

Features:

• High quality imported PP material employed for high stability and no chemical reactions with test reagents.
• Compatible with DMSO and inert to water.
• Can be stored under subzero temperature from -40 to -80°C
• Maximum sustainable centrifuge force 4000g.
• Autoclavable at 20Psi, 121°C for 20 minutes, great heating uniformity.
• Minimum residual liquid, low heavy metal content.
• Certified DNase/RNase and Pyrogen Free.
• Conformed to international SBS Standards.
• Good flat and can be transported for long distance if sealed by heat sealable film.
• Produced and packed in Class 100,000 clean workshop.
• Alphabetical sorting and corner cut marking for convenient tracking of samples.
• Each package has a separate article number/batch number identification, facilitating the quality tracking.

Application:

Genomic DNA extraction, plasmid DNA extraction, and purification of various samples. High-throughput automatic liquid operation to achieve high-throughput operations, such as protein precipitation, liquid extraction, and processing of animal tissues, bacteria, plants, soil, clinical samples, yeasts, etc.

PCR 96-Well Plates

Features:

• Made of high-quality polypropylene to ensure minimal loss of reaction solution.
• Flat surface, thick and solid, not easy to deform.
• The black ink-printing marks on the surface are easy to read and identify.
• Elevated edge of the hole can better prevent cross contamination.
• Compatible with NEST pressure sensitive film, self-adhesive film and hot sealing film.
• Autoclavable.
• The tube wall of transparent 96-well PCR Plate is thin, allowing for good light transmission.
• White PCR 96-well plate is better for qPCR experiments.
• The maximum capacity of the 0.1mL tube is 150 µL, and that of a 0.2 mL tube is 250 µL.
• Certified DNase/RNase and Pyrogen Free.

Further details on ELISA, Deep Well, and PCR 96-Well Plates:

Vector Laboratories – VECTASHIELD® Antifade Mounting Media

Choosing an effective mounting medium is especially important for immunofluorescence imaging. Fluorophores are susceptible to photobleaching and fading from both the imaging excitation light and during storage. The right mounting medium will protect your samples for short- and long-term use and archiving. VECTASHIELD^® Antifade Mounting Media formulations offer unsurpassed protection against fading and photobleaching.

Key Advantages

• Inhibits photobleaching of most fluorophores, dyes, fluorescent proteins and stains
• Ideal refractive index
• Easy to use, no warming necessary
• Continues to inhibit photobleaching even after prolonged storage of mounted slides
• With or without nuclear or cytoskeletal counterstain
• Hardening or non-hardening formulations
   

abc biopply - Humanized Disease Models: Boosting 3D Drug Development Models to the ex vivo

Over the last decade, abc biopply has pioneered a unique portfolio of 3D multi-organoid in chip assays that perfectly mimic the physiological microenvironment. The proprietary technology enables the easy and reliable generation of quantitative datasets permitting powerful and predictive statistics. The assays and the related CRO services support pharmaceutical and biotech companies to de-risk their drug development processes. With this development, abc biopply has successfully boosted the relevance of purely in vitro testing to the ex vivo level.

Services
abc biopply offers a comprehensive portfolio of validated service packages based on the proprietary 3D CoSeedis in chip communication technology^™. Utilizing 3D CoSeedis humanized multi-organoid models^™, as well as traditional monolayer models, they specialize in assay endpoints useful for drug discovery and pharmaceutical development.

Micronic - Rack Reader DR900

The high speed Micronic Rack Reader DR900 reads whole racks filled with 2D Data-Matrix coded tubes in just 3 seconds. With the optional added 1D Side Barcode Reader, it can also read 1D Barcodes simultaneously in just 1 second. The Rack Reader DR900 works with the easy to install Micronic Code Reader Software which integrates into any laboratory sample database.

• Reads and decodes racked tubes in 3 seconds
• Compatible with a variety of 2D Data-Matrix coded tube brands
• Reads and decodes 2D Data-Matrix coded tubes
  in 138-, 96-, 48-, and 24-well format
• Compact and user-friendly
• Comes with a 5-year warranty

USA Scientific – TipOne® Pipette Tip Starter Systems

Starter systems are a convenient way to get started with TipOne^®.

Each TipOne^® starter system includes 10 racks with tips and 20 refill wafers (2880 tips).

USA Scientific – TipOne® Filter Tip Refill Starter Systems

Filter tip starter systems are a convenient way to get started with TipOne^® filter tip refills.  Each TipOne^® filter tip refill starter system includes 10 racks with tips and 10 refill cassettes (1920 tips).  All tips are certified free of detectable RNase, DNase, DNA and pyrogens.

USA Scientific – TipOne® Pipette Tips

TipOne^® is the original easy-to-load, refillable tip system that saves space and reduces waste.  They are reusable, easy to refill, and will last through repeated autoclaving cycles.  Refills are sealed in plastic; USA Scientific doesn't use cardboard, paper, or other uncharacterized materials as tip containers.

Associates of Cape Cod, Inc. – PyroSmart NextGen®

Make An Impact – The Future of Sustainable LAL testing is bright!

Click here to watch the launch video! (youtube.com)

PyroSmart NextGen^® is a sustainable recombinant Cascade Reagent (rCR) that delivers
the same reliable results as your conventional LAL reagent, while offering these additional advantages:

• No Animal Content – Horseshoe Crab Blood Free
• Same Cascade
• No Cross Reactivity With 1,3-ß-D-glucans
• Same Instrument
• Same Preparation Steps
• Meets Your Sustainability Objectives - Keep Your Method

Click here for more information.
Click here to order or request a quote.

Read the BPB report on the Evaluation of Recombinant Cascade Reagent PyroSmart NextGen^®
and Limulus Amebocyte Lysate Equivalency in a Plate and Tube Reader for Bacterial Endotoxins Testing. 
Click here to read the report.

Aqua Solutions – Solutions for Laboratory Water Purification

Go for user-friendliness with Aqua Solutions. These systems are easy to install, operate, and maintain.

Product lines include:
• Type I Reagent Grade DI systems
• Type II & Type III Reagent Grade DI systems
• Combination Reverse Osmosis plus Type I DI systems in a single cabinet design
• Combination Reverse Osmosis plus Type II/III DI systems in a single cabinet design
• Reverse Osmosis pretreatment systems
• Replacement cartridges and accessories for other systems

Click here for more information.
Click here to order or request a quote.

EpiCypher – CUTANA™ CUT&Tag Kit: Powerful Assays for Epigenomic Profiling

Ultra-sensitive. Rapid results. Rigourously tested.

Advantages include:

• Streamlined two-day protocol with no library prep
• Exclusive single-tube workflow maximizes yield
• Reliable profiling using low cell numbers
• Dramatically reduced assay costs
• Comprehensive kit goes from cells to sequence-ready DNA

Click here to order or request a quote.
Click here for more information.

Vector Laboratories – VectaMount® Express Mounting Medium

Save time, money, and reduce waste by enabling mounting directly after staining!











VectaMount Express is a non-aqueous clearing and mounting medium enabling the rapid mounting
of cell and tissue specimens following immunohistochemistry (IHC) staining.

Click here to order or request a quote.
Click here for more information.

ErgoOne® Single, Eight and Twelve-Channel Pipettors

• Works with TipOne^® and other universal tips
• Colour-coded by volume, easy to calibrate in the lab, and are fully autoclavable
• Light, balanced weight reduces fatigue
• Centrally located 4-digit display increases precision
• Plunger height accommodates large and small hands
• Volume adjustment and locking easily achieved with one hand
• Ejector button position reduces strain
• 3 year warranty

EpiCypher – CUTANA™ ChIC/CUT&RUN Kit

Includes all the controls you need for a well-designed publication-quality experiment!

This kit enables streamlined chromatin profiling of histone post-translational modifications (PTM) and chromatin associated proteins while providing increased throughput and reproducibility with multi-channel pipetting.

• Control Antibodies
  Lot-tested positive and negative control antibodies generate reliable CUT&RUN data and display strong correlation with ChIP-seq. Kit includes clear instructions for their application in CUT&RUN.
• E. coli Spike-in DNA
  Monitor DNA loss and/or amplification during library preparation to normalize sequencing data and perform pairwise comparisons.
• Spike-in Nucleosome Controls
  First-in-class, defined DNA-barcoded nucleosome controls for CUT&RUN.
  Combine with positive and negative control antibodies to monitor and quantify experimental success. 

Click here for more information.
Click here to watch the video.
Click here to order or request a quote.