New Products

EpiCypher - SNAP-ChIP™ Sample Normalization and Antibody Profiling for ChIP

SNAP-ChIP uses DNA barcoded recombinant designer nucleosomes (dNucs) as next-generation spike-ins for Chromatin Immunoprecipitation (ChIP). The first product in this family (the K-MetStat, or lysine-methylation status panel) consists of a pool of dNucs carrying fifteen well-studied histone lysine methyl marks and an unmodified control. EpiCypher's K-MetStat panel can easily be added to any ChIP workflow without altering the protocol. However, users can monitor antibody specificity and evaluate technical variability within a ChIP or ChIP-seq experiment for the first time, setting SNAP-ChIP apart from any other spike-in controls (i.e. Drosophila) currently available.

 

 

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NuGEN - Unique Indexing Solutions for Illumina’s High Capacity Sequencing Platforms

NuGEN’s Unique Dual Indexes are designed to enable researchers to take full advantage of the latest generation of Illumina sequencers.   They detect index hopping, a sequencing phenomenon that can lead to mis-assignment of reads to the incorrect sample. Use of an additional index can enable the detection and eliminate mis-assigned reads from a dataset. This is particularly critical in applications that require high sensitivity, and improves accuracy of sample assignment in any experiment. Index hopping has been shown to occur at a higher frequency in patterned flow cell sequencing platforms, such as the HiSeq 3000, HiSeq 4000, NovaSeq.

The Unique Dual Indexes are conveniently configured in a pre-plated format as 96 unique barcode pairs, so manual preparation of barcode pairs is completely eliminated. Simply add the adaptor to the sample and ligate, and each sample will have index1 and index2 barcodes that are completely unique from all other samples in the plate.

This feature is currently available for the Ovation® Ultralow System V2 for DNA-Seq library preparation, and for the Universal Plus mRNA-Seq and Trio RNA-Seq system for preparation of RNA-Seq libraries. Solutions for the Methyl-Seq product line will also be available soon.

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Heathrow Scientific – Universal Pipette Wall Mount

The pipette holder comes with two wall mounting brackets that can hold two pipettes each and is supplied with different colored upper and lower segments, that easily slide into place. This enables labs to color code their pipette holders for quick identification purposes, or a user can personalize the holder in the colors of their choice.

Once mounted, the pipette holder can securely hold virtually every known brand of pipette. Inserts on the upper segments can be added or removed to accommodate the fit of various pipette widths. One handed removal or replacement of pipettes is made easy with the segments unique design that includes traction grips that help center and hold the pipettes in a vertical position which helps eliminate potential contamination.

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Micronic – Tissue Tubes with External Threads

Designed with special features for the storage of fresh frozen tissue, these tissue tubes have a wide opening for easy loading and are shallow for the removal of tissue samples using tweezers.  Of course, liquid samples can also be securely stored in these new tubes.

  • Triple start screw thread for optimal sealing quality
  • Improved sample integrity due to external thread
  • Thick tube walls, sturdy design
  • Excellent properties for low temperature storage
  • Code surface has a raised edge to protect the 2D code
  • Black code surface cannot be separated from the transparent tube
     

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HumanZyme – HumanKine® Interferon Beta

High-quality, tag-free, Xeno- and animal product-free recombinant human IFN beta expressed from HEK293 cells.

The glycosylation of IFN beta has been shown to be essential to its activity and stability, both in vitro and in vivo. IFN beta expressed in human cells assures native processing, glycosylation and folding, preserving its biologic function and activity.  
 

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Anatrace – Super Heparin Agarose HP Resin

Fast, reliable and high quality affinity purification.

Immobilized heparin is used to purify native or recombinant proteins eg. enzymes such as lipases, plasma coagulation proteins, lipoproteins, growth factors, nucleic acid binding proteins such as transcription factors, DNA & RNA polymerase, hormone receptors, serine proteases inhibitors and extracellular matrix proteins such as fibronectin, laminin and collagens etc.

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Hycult Biotech - New Antibodies and Proteins for Immunity Research

Hycult is continuously developing new antibodies and proteins for research in innate immunity, inflammation, complement pathways and more.  Here are their newest products:

Click here for a complete list of new products added to the Hycult portfolio in 2017. 

Heathrow Scientific – Pearl Pipette Starter Kit

A convenient kit for new labs or for customers looking for a new set of pipettors covering the most commonly used volumes.

Pearl Pipettes were specifically engineered for ease of use and comfort. The sleek, ergonomic design and reduced plunger pressure help reduce the chance of Repetitive Stress Injury (RSI), as the pipettes require 2/3 the operation pressure of most standard pipettes. Each pipette is tested in accordance with standards and a calibration certificate is supplied. Manufactured in accordance with ISO08655 and GLP regulations.

The kit includes 3 single channel Pearl Pipettes (2 – 20µL; 20 – 200µL; 100 – 1000µL), a Universal Carousel Pipette Stand and 5 Reagent Reservoirs-all at a VALUE PRICE!

 

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Vector Laboratories - ImmPRESS™ Duet Double Staining Polymer Kits

This kit enables fast, well-defined localization and visualization of two different target antigens on the same tissue section. Utilizing Vector’s unique ImmPRESS™ micropolymer chemistry, they independently conjugate highly-active horseradish peroxidase (HRP) and alkaline phosphatase (AP) enzyme polymers to anti-mouse IgG and anti-rabbit IgG affinity-purified, highly cross-adsorbed secondary antibodies. These reagents are then blended at optimized dilutions to provide a stable pre-diluted, ready-to-use HRP/AP formula that will detect mouse and rabbit primary antibodies, and facilitate a time-saving, simplified, one-step double label detection protocol. For maximum sensitivity and staining contrast between target antigens, ImmPACT™ DAB EqV (HRP, brown) and ImmPACT™ Vector® Red (AP, magenta) substrates are included to complete this easy to use staining kit.

Click here for more information. (Link to Vector website)
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EpiCypher – EpiDyne™ Nucleosome Remodeling Substrate

Defined nucleosome substrates to study disease-relevant ATP-dependent chromatin remodeling complexes.

Nucleosome remodeling regulates DNA access on chromatin and thus impacts gene expression and genome repair. Many ATP-dependent remodeling enzymes are associated with human disease but are challenging targets to study biochemically due to the requirement for nucleosome-based substrates. EpiCypher has addressed this need by developing EpiDyne™ recombinant nucleosome substrates to monitor nucleosome remodeling activity in vitro.

Technical Note: Nucleosome Remodeling Assay by Restriction Enzyme Accessibility

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Labnet – Digital Dry Baths

  • Single, dual and four block capacity
  • Broad temperature range up to 150°C, which makes them useful for a variety of applications in molecular biology, histology, clinical, environmental, and industrial laboratories
  • Two bright LED displays for quick reference of temperature and cycle time
  • USB connectivity enables traceability of data

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AthenaES – PiCOEXPLORER™ Handheld Photometer

  • A low-cost portable analytical tool
  • Suitable for quantitative colorimetric or optical density measurements
  • Controlled through wireless communication to a tablet, smartphone or other mobile device
  • No special cuvettes needed - assays can be performed in a close tube, thereby reducing the potential for contamination or spillage

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Sunrise Science Products – Yeast Media Building Tool

Sunrise offers hundreds of selective and non-selective yeast media formulations.  Their commitment to customization makes it easy to change or remove sugars, nitrogen, amino acids, salts, metals or anything else. Use the Build Media Tool on the Sunrise website to modify an existing media formula, or build your own from scratch. 


Click here for the Build Media Tool (Link to Sunrise Website)

Mirus – Label IT® MFP488 Nucleic Acid Labeling Reagent

MFP488 provides a more robust option for nucleic acid labeling than traditional fluorescein methods.

  • High Photostability – Facilitates longer time for observation and image capture
  • Widespread Instrument Compatibility – Spectrally similar to fluorescein
  • Stable at Low pH – Fluorescence is maintained over a broad range (pH 4-9)



Click here for more information.  (Link to Mirus Website
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Click Image to Enlarge:  Label IT® MFP488 Labeled Plasmid DNA is More Resistant to the Effects of Low pH as Compared to Label IT® Fluorescein Labeled Plasmid DNA. Plasmid DNA was labeled at a low density, 1 label per 65 bp, using Label IT® MFP488 or Label IT® Fluorescein Nucleic Acid Labeling Kits. Purified DNA was subsequently diluted in various pH buffers (50 mM HEPES, pH 8, 100 mM MES, pH 5.4, and 100 mM MES, pH 3). Fluorescence was measured using a Tecan Genios Fluorometer and normalized to the respective control measured at 50 mM HEPES, pH 8.

Micronic – 0.30mL 2D-Coded Tubes with External Thread

  • 0.30mL tubes with a working volume of 0.21mL
  • Available in bulk or Micronic 96-1 Rack
  • Compatible with the Univo range of Screw Cap Recappers.
  • External threads eliminate the possibility of the sample coming into contact with the screw thread, minimizing chances of cross-contamination while improving sample integrity
  • Caps available in 6 different color



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NuGEN – Trio RNA-Seq

Trio RNA-Seq provides a highly sensitive whole transcriptomics solution that is ideally suited for applications with low abundance transcripts, such as detection of viral transcripts or biomarker assessment in liquid biopsy samples.

  • Consistent performance from wide input range - High quality data from as low as 500 pg
  • Unbiased transcript coverage
  • Excellent results from FFPE and/or degraded samples

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Hycult Biotech – Pig Complement Pathway Assays

The Pig Classical and Lectin Complement Pathway ELISAs are easy-to-use and specific per pathway by making use of a combination of specialized coatings and buffers. Complement deficiencies or other defects in the complement system can easily be screened by running an assay for each pathway in parallel or separately.  The pig platform is ideal for use as a model for transplantation research.

  • Classical Complement Pathway
  • Lectin Complement Pathway

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Jena Bioscience - Linker-optimized Cy3- and Cy5-modified dUTPs

Labeling of DNA probes for in situ hybridization is most often performed by enzymatic incorporation of labeled dUTP using Taq DNA polymerase.  The new linker-optimized Cy3- and Cy5-modified dUTPs possess a longer linker resulting in higher labeling efficiencies at similar substitution rates.

  • Recommended for direct enzymatic labeling of DNA/cDNA e.g. by PCR and Nick Translation
  • Incorporated as substitute for its natural counterpart dTTP
  • The resulting Dye-labeled DNA/cDNA probes are ideally suited for fluorescence hybridization applications such as FISH or microarray-based gene expression profiling

Click here for more information (Link to Jena Bioscience website)
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NuGEN - Universal Plus mRNA-Seq

Universal Plus mRNA-Seq is a comprehensive solution for mRNA sequencing with the unique option to eliminate unwanted transcripts from the library. 

  • Broad dynamic input range from 1 ug to as low as 10 ng, enables access to previously inaccessible low input samples
  • Efficient library construction with minimal adaptor dimers enabled by proprietary DimerFree technology
  • Customizable transcript depletion with AnyDeplete maximizes informative data from mRNA sequencing

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Micronic – TPE Push Caps RB

In addition to the current TPE Push Caps, which are manufactured from Medical approved material (USP Class VI certificate), Micronic now launches the TPE Push Caps RB in a Capcluster-96 and Capband-8 format. Since the raw material used for the TPE Push Caps RB does not have to meet the medical grade standards, this product is a highly cost effective solution for most research applications. These caps are currently only available in 'Natural'.

  • Manufactured and assembled in a certified Class 7 Clean Room
  • RNase/DNase/Pyrogen free
  • Reliable delivery times
  • Superior sealing down to -80°C
  • Minimal evaporation
  • Compatible with manual and electric Push Cap equipment

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Vector Laboratories – Cyanine Dye Conjugated Lectins

  • More robust and intense fluorescence compared with Vector’s existing traditional fluorophore conjugates
  • Intended to be used to identify glycoprotein expression on cells and tissue sections
  • Applications therefore include immunofluorescence and flow cytometry

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Image: Colon (FFPE): Antigen retrieved with Antigen Unmasking Solution, stained with Cy5 Sambucus Nigra Lectin (SNA; fuchsia). DAPI counterstain (blue).

Heathrow Scientific – Low Temp PCR Rack 96 Well

  • Unique sliding lid that flips to become a stand
  • Ambidextrous lid can be switched to accommodate left or right orientation
  • Closed base design helps samples stay cold longer
  • Can be used for freezer storage down to -80°C
  • Holds 0.2mL tubes or tube strips

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Vector Laboratories - VectaFluor™ Duet Immunofluorescence Double Labeling Kits

  • Ready-to-use format offers maximum convenience to achieve immunofluorescence double labeling in one step.
  • Kit includes a detection reagent that will detect mouse and rabbit primary antibodies with green and red DyLight® fluorescent dyes in a single step.
  • Affinity purified, extensively cross-adsorbed secondary antibodies are conjugated to DyLight® dyes in a manner that ensures maximum degree of labeling without compromising antibody affinity or specificity.
  • Compatible with fluorescence staining of cells and tissues.
     

Click here for more information. (Link to Vector Laboratories website)
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MagBio - cfKapture™ 21 Isolation Kit for Circulating Cell-free DNA (ccfDNA) from Stabilized Plasma

  • Allows plasma sample storage at room temperature for 21 days before processing
  • Not necessary to rush plasma purification.  Large volume users can separate plasma and process samples without plasma sample degradation.
  • Efficient ccfDNA isolation – No carrier RNA
  • Can be used with any blood collection tube (Streck BCT, PAXGene cfDNA tubes, EDTA).  For best results, use in conjunction with Blood STASIS™ 21-ccfDNA tubes.


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MagBio - Blood STASIS™ 21-ccfDNA Blood Collection Tubes

  • Room temperature sample transport and storage for up to 21 days
  • Stabilization of circulating cell-free DNA (ccfDNA)
  • Direct draw blood tube for collection, stabilization, transport and storage

The Blood STASIS™ 21-ccfDNA is a plastic, evacuated tube used for collection, anti-coagulation, stabilization, transport, and storage of venous whole blood as well as the preservation of circulating cell-free DNA (ccfDNA).

 

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Jena Bioscience - Short LCP Lipids for Membrane Protein Crystallization

Crystallization in the Lipidic Cubic Phase (LCP) has evolved into an important method for crystallization of membrane proteins, with the lipid Monoolein being the first choice to create a stable LCP. In the past few years however, the short lipids (7.7 MAG, 7.8 MAG, 7.9 MAG) have become increasingly popular and the recent progress in applying the highly viscous lipidic cubic phase for serial femtosecond crystallography (LCP-SFX) further accelerates the success of the LCP method by:

  • Delivering the crystal-loaded viscous LCP directly into the XFEL beam (thereby reducing sample consumption in comparison to liquid injectors)
  • Taking advantage of the inherently small crystals grown in LCP
  • Avoiding tricky crystal mounting from LCP
     

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Vector Laboratories – Cy3 and Cy5 Conjugated Secondary Antibodies and Streptavidin

These fluorescent dyes generate a brighter signal and are more photostable than traditional fluorophores. Cy3 emits in the visible red spectra, and can be paired with DyLight® 488 or fluorescein (green) conjugates, for example, for double fluorescent staining. Cy5 is most optimally used with confocal microscopy, and can be used in combination with Cy3 or other contrasting fluorophores.

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Vector Laboratories - ProtOn HRP (Peroxidase) Antibody and Protein Labeling Kit

  • The ProtOn™ HRP Protein Labeling Kit is designed for simple and fast labeling of proteins with Horseradish Peroxidase (HRP)
  • The kit is ideally suited to label antibodies or other proteins
  • HRP is activated under precise conditions to generate an optimal number of reactive aldehyde groups for subsequent conjugation with amine-containing molecules via reductive amination
  • Conjugation of the HRP is accomplished through reaction with primary amine on lysine residues or terminal amino groups on target proteins to form a stable secondary amine linkage.

Click here for more information. (Link to Vector website)
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HumanZyme - Wnt3A Expressed From Human Cells

HumanZyme offers recombinant human Wnt3A expressed from human cells. Wnt3a is a widely used reagent for the in vitro self-renewal and differentiation of human embryonic stem cell cultures, and HumanZyme is now one of a very few suppliers who offer HEK293-expressed Wnt3A.

  • Animal-derived product free
  • High Activity
  • Lyophilized and Carrier Free (CF)

Click here for more information. (Link to HumanZyme website)
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Heathrow Scientific – Silicone Lab Mats

  • Reusable, reliable and reversible
  • Made from FDA food grade silicone
  • Ideal for every type of laboratory and more specialized areas such as cold rooms, clean rooms, sterile suites and areas where high sterility is a requirement
  • Protect countertops from hot items up to 200°C (392°F)
  • General chemical resistance from moderate oxidizing chemicals, concentrated sodium hydroxide  - NOT RESISTANT to many solvents, oils, concentrated acids and dilute sodium hydroxide
  • Washable with standard disinfectants in sinks or dishwashers allow for easy clean-up for repetitive uses
  • Mat can be rolled up for compact storage
  • Autoclavable at 121° for 15 minutes

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Micronic – Univo Screw Cap Recapper SR024

  • Caps or decaps 24 Screw Cap tubes at once in less than 30 seconds
  • Compatible with the Micronic range of 24-format tubes (6.00mL)
  • Precise torque value for optimal sealing quality
  • No adapters required
  • Easy-to-use graphical touch screen interface for labware selection

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Micronic – Externally Threaded Sample Tubes

The new 0.75ml and the 1.40ml tubes with external thread carry the same outstanding qualities as the internally threaded tubes, but are complemented with additional features:

  • Using externally threaded tubes for sample storage eliminates the possibility of the sample coming into contact with the screw thread, minimizing chance of cross-contamination while improving sample integrity. Due to thick tube walls, the tube has a sturdy design and excellent properties for ultra-low temperature storage.
  • The sample tubes can hold a higher (net) volume of material while occupying the same amount of storage space, maximizing storage volume.
  • The triple thread of the externally threaded tubes gives an excellent closure and horizontal placement of the cap to ensure long-term sample preservation and storage. For better handling, the screw cap has an outside grip. The caps are available in 6 different colors.
  • The code surface of the tubes with external thread features a raised edge, which protects the 2D code against accidental scratches, ensuring absolute traceability.

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Heathrow Scientific – Universal Pipette Stand

Hold and store pipettes in style with the new universal pipette stand that holds up to 8 single channel, 4 multi channel, or a combination of both pipettes. A sleek and modern design enables this stand to securely hold virtually every known brand of pipette in the marketplace making it truly ‘universal’ while adding a pop of color to a bench top.

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Heathrow Scientific – Pipette Controller

Comfortable to hold and easy to use, the manual inline pipette controller was designed with an ergonomic grip and bulb for simple and precise operation. A “T” bar thumb lever controls the aspirating and dispensing speeds from serological pipettes from 1 to 100 mL in size.

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Micronic – Extended Compatibility Screw Cap Recappers

Due to the great success of the Micronic Univo Screw Cap Recapper SR008 and SR096, Micronic now offers both models for use with other brands of tubes and caps. The compatible brands are:

  • Thermo Scientific Matrix
  • LVL Technologies
  • FluidX
  • Other brands are available upon request

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Micronic - Univo Screw Cap Recapper SR048

  • Extremely durable design for reliable operation
  • Caps or decaps 48 Screw Cap tubes at once in less than 30 seconds
  • Compatible with Micronic 48-well format tubes (4.00ml)
  • Precise torque value for optimal sealing quality
  • No adapters required
  • Easy-to-use graphical touch screen interface

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Mirus - TransIT®-Lenti Transfection Reagent

Designed to enhance delivery of packaging and transfer vectors to adherent HEK 293T cell types and increase recombinant lentivirus production.

  • High Performance – Provide up to eight-fold higher functional titers
  • Simple Protocol – No media change required, single harvest
  • Animal Origin Free – Regulatory friendly

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Micronic – Amber Polypropylene Storage Tubes

  • Designed from special amber coloured Polypropylene to eliminate sample degradation by exposure to light while still allowing visibility of the enclosed sample
  • Ensures the integrity of light sensitive biological samples even over long-term storage periods when used in conjunction with a secure screw cap or push cap
  • Available in Non-coded and laser encrypted 2D Data-Matrix coded formats

Click here for more information on non coded tubes.
Click here for more information on 2D coded tubes.
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Labnet – Rocker 35 EZ Large Capacity Lab Rocker

Designed for durability in laboratories requiring a larger platform area and precise control over rocking parameters

  • Both speed and time are easily selectable and the analog control has been upgraded to display discreet values
  • Easily adjustable tilt with knob on side
  • Can easily handle up to 11 pounds or 5 kg of load so a double platform can be fully loaded without any variation to speed
  • 5 year warranty

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